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Coffee and Parkinson’s Disease: Effective for Prevention, but Caution Is Needed for Patients
Coffee is a familiar daily beverage for millions of people around the world. Scientists have extensively studied its relationship with Parkinson’s disease, one of the most common neurodegenerative disorders. This raises an important question: Does coffee really help prevent Parkinson’s disease? And should people who already have Parkinson’s drink coffee?

Caffeine: A Natural Shield Protecting the Brain Against Parkinson’s Disease
Numerous large-scale studies worldwide have revealed a notable finding: regular coffee drinkers have a significantly lower risk of developing Parkinson’s disease compared to non-coffee drinkers.
This protective effect is largely explained by the role of caffeine, the main active compound in coffee. Caffeine can inhibit adenosine A2A receptors in the brain, a mechanism currently being applied in the development of Parkinson’s medications. In other words, caffeine acts as a natural neuroprotective agent, helping shield nerve cells from degeneration.
A Breakthrough Discovery Involving the LRRK2 Gene Mutation
A groundbreaking study published in the scientific journal Neurology by researchers from Massachusetts General Hospital (USA) provided even stronger evidence of caffeine’s role.
The study focused on mutations in the LRRK2 gene, a genetic factor known to significantly increase the risk of Parkinson’s disease. Researchers compared 188 Parkinson’s patients with 180 healthy individuals, including participants with and without the LRRK2 mutation.
The results were striking:
Among individuals carrying the LRRK2 mutation, those with Parkinson’s disease had up to 76% lower blood caffeine levels compared to healthy individuals. In contrast, the difference in caffeine levels among those without the mutation was only 31%.
Notably, individuals with both the LRRK2 mutation and Parkinson’s disease consumed 41% less caffeine daily than those without the disease, regardless of their genetic status.
For People With Parkinson’s: Should They Drink Coffee or Not?
While coffee’s preventive role appears relatively clear, the answer for those who already have Parkinson’s disease is far more complex.
Different Responses Among Individuals
Clinical studies show that Parkinson’s patients respond very differently to coffee:
Positive responders:
Some patients report reduced tremors, improved alertness, and better concentration after drinking coffee. In these cases, caffeine may help alleviate mild motor symptoms.
Negative responders:
Conversely, many patients experience worsened symptoms such as increased tremors, palpitations, rapid heartbeat, and especially insomnia, a problem already common among people with Parkinson’s disease.

Caffeine Is Not a Treatment for Parkinson’s Disease
It is crucial to emphasize that clinical trials have clearly shown caffeine is not a treatment for Parkinson’s disease. Any reduction in tremors occurs only in a small subset of patients, and even then, the effect is mild and cannot replace standard medical treatments.
Important Considerations for Parkinson’s Patients
Interaction With Medications
One major concern is that caffeine may interfere with the effectiveness of certain Parkinson’s medications, particularly levodopa, the most commonly prescribed drug. Caffeine may affect drug absorption or alter how the medication works in the body.
Differences Between Men and Women
Research also suggests that coffee’s protective effects may vary between men and women due to hormonal influences. In women, caffeine’s effects can change depending on menstrual cycles or menopausal status.
Risk of Insomnia and Anxiety
Excessive coffee consumption especially in the afternoon or evening can cause insomnia, increased heart rate, and anxiety. For Parkinson’s patients who already struggle with sleep disorders, these side effects should be carefully avoided.
Expert Recommendations
Based on current research and clinical experience, experts recommend:
Dosage: If you are accustomed to drinking coffee and do not experience worsening symptoms, you may consume 1–2 small cups in the morning. Do not exceed 3 cups per day.
Timing: Drink coffee only in the morning or before 2:00 PM to avoid sleep disturbances.
Monitor your response: If tremors worsen or you experience palpitations or insomnia, reduce intake or stop drinking coffee.
Consult your doctor: Always discuss your coffee consumption with a neurologist, especially if you are taking Parkinson’s medications.
Listen to your body: Each patient is unique. What works for one person may not work for another.
Goce Coffee: Quality and Safety for Your Health
If you choose to continue drinking coffee, selecting a high-quality, pure source is essential. Goce Coffee offers products made from 100% premium Robusta beans from Vietnam’s Central Highlands, with no additives, preservatives, or artificial flavorings.
With strict production standards and rigorous quality control, Goce Coffee ensures that every cup delivers a pure taste while meeting high safety standards. For health-conscious consumers, choosing the right coffee is a smart decision.

>>> Order now: Goce Black Coffee for free consultation and special offers today.
Parkinson’s disease is a long journey that requires patience, knowledge, and continuous adjustment. Coffee may be part of a healthy lifestyle, but it is only one small piece of the bigger picture. A balanced diet, regular physical activity, quality sleep, and strict adherence to medical treatment remain the most critical factors.
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References:
Thanh Niên Newspaper: “Coffee and Parkinson’s Disease”
Parkinson Vietnam: “Coffee and Parkinson’s: Should You or Should You Not?”
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